Cargando…

Mantle cell lymphoma presenting as acute appendicitis

INTRODUCTION: Most cases of appendicitis associated with lymphoma reported in literature are in patients with Burkitt's or large B-cell lymphoma. Mantle cell lymphoma only makes up 4% of all lymphoma cases in the U.S. We report a case of a patient with mantle cell lymphoma presenting with acute...

Descripción completa

Detalles Bibliográficos
Autores principales: Chae, Max, Kumar, Sampath, Cheema, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334643/
https://www.ncbi.nlm.nih.gov/pubmed/25506848
http://dx.doi.org/10.1016/j.ijscr.2014.10.068
_version_ 1782358223670476800
author Chae, Max
Kumar, Sampath
Cheema, Muhammad
author_facet Chae, Max
Kumar, Sampath
Cheema, Muhammad
author_sort Chae, Max
collection PubMed
description INTRODUCTION: Most cases of appendicitis associated with lymphoma reported in literature are in patients with Burkitt's or large B-cell lymphoma. Mantle cell lymphoma only makes up 4% of all lymphoma cases in the U.S. We report a case of a patient with mantle cell lymphoma presenting with acute appendicitis. PRESENTATION OF CASE: A 75 year old male with a history of left cervical lymphadenopathy biopsied to be mantle cell lymphoma presented with right lower abdomen pain for 3 days. An outpatient CT scan revealed acute appendicitis. Laparoscopic appendectomy was performed without any complication. The histologic examination showed mantle cell lymphoma occluding the lumen of appendix. DISCUSSION: Typically, appendicitis is caused by obstruction of the lumen of appendix by fecalith or lymphoma. A previously reported case of a patient with mantle cell lymphoma who developed appendicitis received chemotherapy before appendectomy. The author could not determine how mantle cell lymphoma contributed to appendicitis because the lumen of appendix was not occluded by the lymphoma, likely from cytoreduction from chemotherapy. We have a patient with mantle cell lymphoma before the patient received chemotherapy who presented with appendicitis. The appendiceal specimen shows the lumen filled with mantle cell lymphoma. CONCLUSION: This is a rare case of mantle cell lymphoma causing obstruction of appendiceal lumen and subsequently appendicitis, unaffected by chemotherapy.
format Online
Article
Text
id pubmed-4334643
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-43346432015-03-03 Mantle cell lymphoma presenting as acute appendicitis Chae, Max Kumar, Sampath Cheema, Muhammad Int J Surg Case Rep Article INTRODUCTION: Most cases of appendicitis associated with lymphoma reported in literature are in patients with Burkitt's or large B-cell lymphoma. Mantle cell lymphoma only makes up 4% of all lymphoma cases in the U.S. We report a case of a patient with mantle cell lymphoma presenting with acute appendicitis. PRESENTATION OF CASE: A 75 year old male with a history of left cervical lymphadenopathy biopsied to be mantle cell lymphoma presented with right lower abdomen pain for 3 days. An outpatient CT scan revealed acute appendicitis. Laparoscopic appendectomy was performed without any complication. The histologic examination showed mantle cell lymphoma occluding the lumen of appendix. DISCUSSION: Typically, appendicitis is caused by obstruction of the lumen of appendix by fecalith or lymphoma. A previously reported case of a patient with mantle cell lymphoma who developed appendicitis received chemotherapy before appendectomy. The author could not determine how mantle cell lymphoma contributed to appendicitis because the lumen of appendix was not occluded by the lymphoma, likely from cytoreduction from chemotherapy. We have a patient with mantle cell lymphoma before the patient received chemotherapy who presented with appendicitis. The appendiceal specimen shows the lumen filled with mantle cell lymphoma. CONCLUSION: This is a rare case of mantle cell lymphoma causing obstruction of appendiceal lumen and subsequently appendicitis, unaffected by chemotherapy. Elsevier 2014-11-21 /pmc/articles/PMC4334643/ /pubmed/25506848 http://dx.doi.org/10.1016/j.ijscr.2014.10.068 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Article
Chae, Max
Kumar, Sampath
Cheema, Muhammad
Mantle cell lymphoma presenting as acute appendicitis
title Mantle cell lymphoma presenting as acute appendicitis
title_full Mantle cell lymphoma presenting as acute appendicitis
title_fullStr Mantle cell lymphoma presenting as acute appendicitis
title_full_unstemmed Mantle cell lymphoma presenting as acute appendicitis
title_short Mantle cell lymphoma presenting as acute appendicitis
title_sort mantle cell lymphoma presenting as acute appendicitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334643/
https://www.ncbi.nlm.nih.gov/pubmed/25506848
http://dx.doi.org/10.1016/j.ijscr.2014.10.068
work_keys_str_mv AT chaemax mantlecelllymphomapresentingasacuteappendicitis
AT kumarsampath mantlecelllymphomapresentingasacuteappendicitis
AT cheemamuhammad mantlecelllymphomapresentingasacuteappendicitis