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Mantle cell lymphoma presenting as acute appendicitis
INTRODUCTION: Most cases of appendicitis associated with lymphoma reported in literature are in patients with Burkitt's or large B-cell lymphoma. Mantle cell lymphoma only makes up 4% of all lymphoma cases in the U.S. We report a case of a patient with mantle cell lymphoma presenting with acute...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334643/ https://www.ncbi.nlm.nih.gov/pubmed/25506848 http://dx.doi.org/10.1016/j.ijscr.2014.10.068 |
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author | Chae, Max Kumar, Sampath Cheema, Muhammad |
author_facet | Chae, Max Kumar, Sampath Cheema, Muhammad |
author_sort | Chae, Max |
collection | PubMed |
description | INTRODUCTION: Most cases of appendicitis associated with lymphoma reported in literature are in patients with Burkitt's or large B-cell lymphoma. Mantle cell lymphoma only makes up 4% of all lymphoma cases in the U.S. We report a case of a patient with mantle cell lymphoma presenting with acute appendicitis. PRESENTATION OF CASE: A 75 year old male with a history of left cervical lymphadenopathy biopsied to be mantle cell lymphoma presented with right lower abdomen pain for 3 days. An outpatient CT scan revealed acute appendicitis. Laparoscopic appendectomy was performed without any complication. The histologic examination showed mantle cell lymphoma occluding the lumen of appendix. DISCUSSION: Typically, appendicitis is caused by obstruction of the lumen of appendix by fecalith or lymphoma. A previously reported case of a patient with mantle cell lymphoma who developed appendicitis received chemotherapy before appendectomy. The author could not determine how mantle cell lymphoma contributed to appendicitis because the lumen of appendix was not occluded by the lymphoma, likely from cytoreduction from chemotherapy. We have a patient with mantle cell lymphoma before the patient received chemotherapy who presented with appendicitis. The appendiceal specimen shows the lumen filled with mantle cell lymphoma. CONCLUSION: This is a rare case of mantle cell lymphoma causing obstruction of appendiceal lumen and subsequently appendicitis, unaffected by chemotherapy. |
format | Online Article Text |
id | pubmed-4334643 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-43346432015-03-03 Mantle cell lymphoma presenting as acute appendicitis Chae, Max Kumar, Sampath Cheema, Muhammad Int J Surg Case Rep Article INTRODUCTION: Most cases of appendicitis associated with lymphoma reported in literature are in patients with Burkitt's or large B-cell lymphoma. Mantle cell lymphoma only makes up 4% of all lymphoma cases in the U.S. We report a case of a patient with mantle cell lymphoma presenting with acute appendicitis. PRESENTATION OF CASE: A 75 year old male with a history of left cervical lymphadenopathy biopsied to be mantle cell lymphoma presented with right lower abdomen pain for 3 days. An outpatient CT scan revealed acute appendicitis. Laparoscopic appendectomy was performed without any complication. The histologic examination showed mantle cell lymphoma occluding the lumen of appendix. DISCUSSION: Typically, appendicitis is caused by obstruction of the lumen of appendix by fecalith or lymphoma. A previously reported case of a patient with mantle cell lymphoma who developed appendicitis received chemotherapy before appendectomy. The author could not determine how mantle cell lymphoma contributed to appendicitis because the lumen of appendix was not occluded by the lymphoma, likely from cytoreduction from chemotherapy. We have a patient with mantle cell lymphoma before the patient received chemotherapy who presented with appendicitis. The appendiceal specimen shows the lumen filled with mantle cell lymphoma. CONCLUSION: This is a rare case of mantle cell lymphoma causing obstruction of appendiceal lumen and subsequently appendicitis, unaffected by chemotherapy. Elsevier 2014-11-21 /pmc/articles/PMC4334643/ /pubmed/25506848 http://dx.doi.org/10.1016/j.ijscr.2014.10.068 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/). |
spellingShingle | Article Chae, Max Kumar, Sampath Cheema, Muhammad Mantle cell lymphoma presenting as acute appendicitis |
title | Mantle cell lymphoma presenting as acute appendicitis |
title_full | Mantle cell lymphoma presenting as acute appendicitis |
title_fullStr | Mantle cell lymphoma presenting as acute appendicitis |
title_full_unstemmed | Mantle cell lymphoma presenting as acute appendicitis |
title_short | Mantle cell lymphoma presenting as acute appendicitis |
title_sort | mantle cell lymphoma presenting as acute appendicitis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334643/ https://www.ncbi.nlm.nih.gov/pubmed/25506848 http://dx.doi.org/10.1016/j.ijscr.2014.10.068 |
work_keys_str_mv | AT chaemax mantlecelllymphomapresentingasacuteappendicitis AT kumarsampath mantlecelllymphomapresentingasacuteappendicitis AT cheemamuhammad mantlecelllymphomapresentingasacuteappendicitis |