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Feedforward regulation of mRNA stability by prolonged extracellular signal-regulated kinase activity

Extracellular signal-regulated kinase (ERK) plays a central role in signal transduction networks and cell fate decisions. Sustained ERK activation induces cell differentiation, whereas transient ERK results in the proliferation of several types of cells. Sustained ERK activity stabilizes the protein...

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Detalles Bibliográficos
Autores principales:	Nagashima, Takeshi, Inoue, Norihiko, Yumoto, Noriko, Saeki, Yuko, Magi, Shigeyuki, Volinsky, Natalia, Sorkin, Alexander, Kholodenko, Boris N, Okada-Hatakeyama, Mariko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Editor's Choice
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334673/ https://www.ncbi.nlm.nih.gov/pubmed/25491268 http://dx.doi.org/10.1111/febs.13172

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