Tissue-nonspecific Alkaline Phosphatase Regulates Purinergic Transmission in the Central Nervous System During Development and Disease

Tissue-nonspecific alkaline phosphatase (TNAP) is one of the four isozymes in humans and mice that have the capacity to hydrolyze phosphate groups from a wide spectrum of physiological substrates. Among these, TNAP degrades substrates implicated in neurotransmission. Transgenic mice lacking TNAP act...

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Detalles Bibliográficos
Autores principales: Sebastián-Serrano, Álvaro, de Diego-García, Laura, Martínez-Frailes, Carlos, Ávila, Jesús, Zimmermann, Herbert, Millán, José Luis, Miras-Portugal, María Teresa, Díaz-Hernández, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2014
Materias:
Mini Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334957/
https://www.ncbi.nlm.nih.gov/pubmed/25709758
http://dx.doi.org/10.1016/j.csbj.2014.12.004

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