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Essential Role for Endogenous siRNAs during Meiosis in Mouse Oocytes

The RNase III enzyme DICER generates both microRNAs (miRNAs) and endogenous short interfering RNAs (endo-siRNAs). Both small RNA species silence gene expression post-transcriptionally in association with the ARGONAUTE (AGO) family of proteins. In mammals, there are four AGO proteins (AGO1-4), of whi...

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Detalles Bibliográficos
Autores principales: Stein, Paula, Rozhkov, Nikolay V., Li, Fan, Cárdenas, Fabián L., Davydenk, Olga, Vandivier, Lee E., Gregory, Brian D., Hannon, Gregory J., Schultz, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335007/
https://www.ncbi.nlm.nih.gov/pubmed/25695507
http://dx.doi.org/10.1371/journal.pgen.1005013