A Parallel Implementation of the Wuchty Algorithm with Additional Experimental Filters to More Thoroughly Explore RNA Conformational Space

We present new modifications to the Wuchty algorithm in order to better define and explore possible conformations for an RNA sequence. The new features, including parallelization, energy-independent lonely pair constraints, context-dependent chemical probing constraints, helix filters, and optional...

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Detalles Bibliográficos
Autores principales: Stone, Jonathan W., Bleckley, Samuel, Lavelle, Sean, Schroeder, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335019/
https://www.ncbi.nlm.nih.gov/pubmed/25695434
http://dx.doi.org/10.1371/journal.pone.0117217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335019/
https://www.ncbi.nlm.nih.gov/pubmed/25695434
http://dx.doi.org/10.1371/journal.pone.0117217

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