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Nuclear Ep-ICD Expression Is a Predictor of Poor Prognosis in “Low Risk” Prostate Adenocarcinomas

INTRODUCTION: Molecular markers for predicting prostate cancer (PCa) that would have poor prognosis are urgently needed for a more personalized treatment for patients. Regulated intramembrane proteolysis of Epithelial cell adhesion molecule results in shedding of the extracellular domain (EpEx) and...

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Detalles Bibliográficos
Autores principales: Assi, Jasmeet, Srivastava, Gunjan, Matta, Ajay, MacMillan, Christina, Ralhan, Ranju, Walfish, Paul G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335027/
https://www.ncbi.nlm.nih.gov/pubmed/25695234
http://dx.doi.org/10.1371/journal.pone.0107586