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Transcriptional Attenuation Controls Macrolide Inducible Efflux and Resistance in Streptococcus pneumoniae and in Other Gram-Positive Bacteria Containing mef/mel(msr(D)) Elements

Macrolide resistance, emerging in Streptococcus pneumoniae and other Gram-positive bacteria, is increasingly due to efflux pumps encoded by mef/mel(msr) operons found on discrete mobile genetic elements. The regulation of mef/mel(msr) in these elements is not well understood. We identified the mef(E...

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Detalles Bibliográficos
Autores principales: Chancey, Scott T., Bai, Xianhe, Kumar, Nikhil, Drabek, Elliott F., Daugherty, Sean C., Colon, Thomas, Ott, Sandra, Sengamalay, Naomi, Sadzewicz, Lisa, Tallon, Luke J., Fraser, Claire M., Tettelin, Hervé, Stephens, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335068/
https://www.ncbi.nlm.nih.gov/pubmed/25695510
http://dx.doi.org/10.1371/journal.pone.0116254