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Mercury Exposure Levels in Children with Dental Amalgam Fillings

Objectives: Mercury combined with other metals to form solid amalgams has long been used in reconstructive dentistry but its use has been controversial since at least the middle of the 19th century. The exposure and body burden of mercury reviews have consistently stated that there is a deficiency o...

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Autores principales: Miriam Varkey, Indu, Shetty, Rajmohan, Hegde, Amitha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335109/
https://www.ncbi.nlm.nih.gov/pubmed/25709298
http://dx.doi.org/10.5005/jp-journals-10005-1261
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author Miriam Varkey, Indu
Shetty, Rajmohan
Hegde, Amitha
author_facet Miriam Varkey, Indu
Shetty, Rajmohan
Hegde, Amitha
author_sort Miriam Varkey, Indu
collection PubMed
description Objectives: Mercury combined with other metals to form solid amalgams has long been used in reconstructive dentistry but its use has been controversial since at least the middle of the 19th century. The exposure and body burden of mercury reviews have consistently stated that there is a deficiency of adequate epidemiological studies addressing this issue. Fish and dental amalgam are two major sources of human exposure to organic (MeHg) and inorganic Hg respectively. Materials and methods: A total of 150 subjects aged between 9 and 14 years were divided into two groups of 75 subjects each depending on their diet, i.e. seafood or nonseafood consuming. Each category was subdivided into three groups based on number of restorations. Scalp hair and urine samples were collected at baseline and 3 months later to assess the organic and inorganic levels of mercury respectively by atomic absorption spectrophotometer (AAS). Results: The mean values of urinary mercury (inorganic mercury) in the group of children with restorations were 1.5915 μg/l as compared to 0.0130 μg/l in the groups with no amalgam restorations (p < 0.001) (Wilcoxon sign rank test and paired t-test). The hair mercury levels (organic mercury) varied signi-ficantly between the fsh-eating group and nonfsh-eating group, the average values being 1.03 μg/l and 0.84 μg/l respectively (p < 0.001) (Mann-Whitney U-test and paired t-test). Conclusion and significance: The notion about the mercury being released from the amalgam restorations as a sole exposure source needs to be put to a rest, as environmental factors collectively overpower the exposure levels from restorations alone. How to cite this article: Varkey IM, Shetty R, Hegde A. Mercury Exposure Levels in Children with Dental Amalgam Fillings. Int J Clin Pediatr Dent 2014;7(3):180-185.
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spelling pubmed-43351092015-02-23 Mercury Exposure Levels in Children with Dental Amalgam Fillings Miriam Varkey, Indu Shetty, Rajmohan Hegde, Amitha Int J Clin Pediatr Dent Research Article Objectives: Mercury combined with other metals to form solid amalgams has long been used in reconstructive dentistry but its use has been controversial since at least the middle of the 19th century. The exposure and body burden of mercury reviews have consistently stated that there is a deficiency of adequate epidemiological studies addressing this issue. Fish and dental amalgam are two major sources of human exposure to organic (MeHg) and inorganic Hg respectively. Materials and methods: A total of 150 subjects aged between 9 and 14 years were divided into two groups of 75 subjects each depending on their diet, i.e. seafood or nonseafood consuming. Each category was subdivided into three groups based on number of restorations. Scalp hair and urine samples were collected at baseline and 3 months later to assess the organic and inorganic levels of mercury respectively by atomic absorption spectrophotometer (AAS). Results: The mean values of urinary mercury (inorganic mercury) in the group of children with restorations were 1.5915 μg/l as compared to 0.0130 μg/l in the groups with no amalgam restorations (p < 0.001) (Wilcoxon sign rank test and paired t-test). The hair mercury levels (organic mercury) varied signi-ficantly between the fsh-eating group and nonfsh-eating group, the average values being 1.03 μg/l and 0.84 μg/l respectively (p < 0.001) (Mann-Whitney U-test and paired t-test). Conclusion and significance: The notion about the mercury being released from the amalgam restorations as a sole exposure source needs to be put to a rest, as environmental factors collectively overpower the exposure levels from restorations alone. How to cite this article: Varkey IM, Shetty R, Hegde A. Mercury Exposure Levels in Children with Dental Amalgam Fillings. Int J Clin Pediatr Dent 2014;7(3):180-185. Jaypee Brothers Medical Publishers 2014 2015-02-09 /pmc/articles/PMC4335109/ /pubmed/25709298 http://dx.doi.org/10.5005/jp-journals-10005-1261 Text en Copyright © 2014; Jaypee Brothers Medical Publishers (P) Ltd. This work is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/
spellingShingle Research Article
Miriam Varkey, Indu
Shetty, Rajmohan
Hegde, Amitha
Mercury Exposure Levels in Children with Dental Amalgam Fillings
title Mercury Exposure Levels in Children with Dental Amalgam Fillings
title_full Mercury Exposure Levels in Children with Dental Amalgam Fillings
title_fullStr Mercury Exposure Levels in Children with Dental Amalgam Fillings
title_full_unstemmed Mercury Exposure Levels in Children with Dental Amalgam Fillings
title_short Mercury Exposure Levels in Children with Dental Amalgam Fillings
title_sort mercury exposure levels in children with dental amalgam fillings
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335109/
https://www.ncbi.nlm.nih.gov/pubmed/25709298
http://dx.doi.org/10.5005/jp-journals-10005-1261
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