Chronic SSRI stimulation of astrocytic 5-HT(2B) receptors change multiple gene expressions/editings and metabolism of glutamate, glucose and glycogen: a potential paradigm shift

It is firmly believed that the mechanism of action of SSRIs in major depression is to inhibit the serotonin transporter, SERT, and increase extracellular concentration of serotonin. However, this undisputed observation does not prove that SERT inhibition is the mechanism, let alone the only mechanis...

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Detalles Bibliográficos
Autores principales: Hertz, Leif, Rothman, Douglas L., Li, Baoman, Peng, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335176/
https://www.ncbi.nlm.nih.gov/pubmed/25750618
http://dx.doi.org/10.3389/fnbeh.2015.00025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335176/
https://www.ncbi.nlm.nih.gov/pubmed/25750618
http://dx.doi.org/10.3389/fnbeh.2015.00025

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