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Dissection of the radical reactions linked to fetal hemoglobin reveals enhanced pseudoperoxidase activity

In the presence of excess hydrogen peroxide (H(2)O(2)), ferrous (Fe(+2)) human hemoglobin (Hb) (α2β2) undergoes a rapid conversion to a higher oxidation ferryl state (Fe(+4)) which rapidly autoreduces back to the ferric form (Fe(+3)) as H(2)O(2) is consumed in the reaction. In the presence of additi...

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Detalles Bibliográficos
Autores principales:	Ratanasopa, Khuanpiroon, Strader, Michael Brad, Alayash, Abdu I., Bulow, Leif
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335259/ https://www.ncbi.nlm.nih.gov/pubmed/25750627 http://dx.doi.org/10.3389/fphys.2015.00039

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