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Whole-Genome Sequence of a Bordetella pertussis Brazilian Vaccine Strain

Despite the reduction in incidence after vaccination, pertussis disease is still considered a public health problem worldwide, mainly due to recent and potential new outbreaks. We report here the complete genome of the Bordetella pertussis Butantan strain used in the Brazilian National Immunization...

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Detalles Bibliográficos
Autores principales: Akamatsu, M. A., Nishiyama, M. Y., Morone, M., Oliveira, U. C., Bezerra, M. F. B., Sakauchi, M. A., Raw, I., Junqueira de Azevedo, I. L. M., Kitajima, J. P., Carvalho, E., Ho, P. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335333/
https://www.ncbi.nlm.nih.gov/pubmed/25700409
http://dx.doi.org/10.1128/genomeA.01570-14
Descripción
Sumario:Despite the reduction in incidence after vaccination, pertussis disease is still considered a public health problem worldwide, mainly due to recent and potential new outbreaks. We report here the complete genome of the Bordetella pertussis Butantan strain used in the Brazilian National Immunization Program as a whole-cell pertussis antigen to compose vaccines such as DTwP (diphtheria, tetanus, and whole-cell pertussis).