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Contribution of the Two Genes Encoding Histone Variant H3.3 to Viability and Fertility in Mice

Histones package DNA and regulate epigenetic states. For the latter, probably the most important histone is H3. Mammals have three near-identical H3 isoforms: canonical H3.1 and H3.2, and the replication-independent variant H3.3. This variant can accumulate in slowly dividing somatic cells, replacin...

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Detalles Bibliográficos
Autores principales:	Tang, Michelle C. W., Jacobs, Shelley A., Mattiske, Deidre M., Soh, Yu May, Graham, Alison N., Tran, An, Lim, Shu Ly, Hudson, Damien F., Kalitsis, Paul, O’Bryan, Moira K., Wong, Lee H., Mann, Jeffrey R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335506/ https://www.ncbi.nlm.nih.gov/pubmed/25675407 http://dx.doi.org/10.1371/journal.pgen.1004964

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