Telomerase Activity in Articular Chondrocytes Is Lost after Puberty

OBJECTIVE: Telomere length and telomerase activity are important indicators of cellular senescence and replicative ability. Loss of telomerase is associated with ageing and the development of osteoarthritis. Implantation of telomerase-positive cells, chondrocytes, or stem cells expressing a normal c...

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Detalles Bibliográficos
Autores principales: Wilson, Brooke, Novakofski, Kira D., Donocoff, Rachel Sacher, Liang, Yan-Xiang Amber, Fortier, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335769/
https://www.ncbi.nlm.nih.gov/pubmed/26069700
http://dx.doi.org/10.1177/1947603514537518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335769/
https://www.ncbi.nlm.nih.gov/pubmed/26069700
http://dx.doi.org/10.1177/1947603514537518

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