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AmgRS-mediated envelope stress-inducible expression of the mexXY multidrug efflux operon of Pseudomonas aeruginosa

AmgRS is an envelope stress-responsive two-component system and aminoglycoside resistance determinant in Pseudomonas aeruginosa that is proposed to protect cells from membrane damage caused by aminoglycoside-generated mistranslated polypeptides. Consistent with this, a ΔamgR strain showed increased...

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Detalles Bibliográficos
Autores principales:	Lau, Calvin Ho-Fung, Krahn, Thomas, Gilmour, Christie, Mullen, Erin, Poole, Keith
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335980/ https://www.ncbi.nlm.nih.gov/pubmed/25450797 http://dx.doi.org/10.1002/mbo3.226

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