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Thrombomodulin/activated protein C system in septic disseminated intravascular coagulation

The thrombomodulin (TM)/activated protein C (APC) system plays an important role in maintaining the homeostasis of thrombosis and hemostasis and maintaining vascular integrity in vivo. TM expressed on vascular endothelium binds to thrombin, forming a 1:1 complex and acts as an anticoagulant. In addi...

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Detalles Bibliográficos
Autor principal: Ikezoe, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336127/
https://www.ncbi.nlm.nih.gov/pubmed/25705426
http://dx.doi.org/10.1186/s40560-014-0050-7