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Thrombomodulin/activated protein C system in septic disseminated intravascular coagulation
The thrombomodulin (TM)/activated protein C (APC) system plays an important role in maintaining the homeostasis of thrombosis and hemostasis and maintaining vascular integrity in vivo. TM expressed on vascular endothelium binds to thrombin, forming a 1:1 complex and acts as an anticoagulant. In addi...
Autor principal: | Ikezoe, Takayuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336127/ https://www.ncbi.nlm.nih.gov/pubmed/25705426 http://dx.doi.org/10.1186/s40560-014-0050-7 |
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