Repurposing Auranofin as a Lead Candidate for Treatment of Lymphatic Filariasis and Onchocerciasis

Two major human diseases caused by filariid nematodes are onchocerciasis, or river blindness, and lymphatic filariasis, which can lead to elephantiasis. The drugs ivermectin, diethylcarbamazine (DEC), and albendazole are used in control programs for these diseases, but are mainly effective against t...

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Detalles Bibliográficos
Autores principales: Bulman, Christina A., Bidlow, Chelsea M., Lustigman, Sara, Cho-Ngwa, Fidelis, Williams, David, Rascón, Jr, Alberto A., Tricoche, Nancy, Samje, Moses, Bell, Aaron, Suzuki, Brian, Lim, K. C., Supakorndej, Nonglak, Supakorndej, Prasit, Wolfe, Alan R., Knudsen, Giselle M., Chen, Steven, Wilson, Chris, Ang, Kean-Hooi, Arkin, Michelle, Gut, Jiri, Franklin, Chris, Marcellino, Chris, McKerrow, James H., Debnath, Anjan, Sakanari, Judy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336141/
https://www.ncbi.nlm.nih.gov/pubmed/25700363
http://dx.doi.org/10.1371/journal.pntd.0003534

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