Cargando…
Screening the Medicines for Malaria Venture "Malaria Box" against the Plasmodium falciparum Aminopeptidases, M1, M17 and M18
Malaria is a parasitic disease that remains a global health burden. The ability of the parasite to rapidly develop resistance to therapeutics drives an urgent need for the delivery of new drugs. The Medicines for Malaria Venture have compounds known for their antimalarial activity, but not necessari...
Autores principales: | Paiardini, Alessandro, Bamert, Rebecca S., Kannan-Sivaraman, Komagal, Drinkwater, Nyssa, Mistry, Shailesh N., Scammells, Peter J., McGowan, Sheena |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336144/ https://www.ncbi.nlm.nih.gov/pubmed/25700165 http://dx.doi.org/10.1371/journal.pone.0115859 |
Ejemplares similares
-
Identification and Validation of a Potent Dual Inhibitor of the P. falciparum M1 and M17 Aminopeptidases Using Virtual Screening
por: Ruggeri, Chiara, et al.
Publicado: (2015) -
A metal ion–dependent conformational switch modulates activity of the Plasmodium M17 aminopeptidase
por: Webb, Chaille T., et al.
Publicado: (2022) -
Mapping the substrate specificity of the Plasmodium M1 and M17 aminopeptidases
por: Malcolm, Tess R., et al.
Publicado: (2021) -
Fingerprinting the Substrate Specificity of M1 and M17 Aminopeptidases of Human Malaria, Plasmodium falciparum
por: Poreba, Marcin, et al.
Publicado: (2012) -
Sitagliptin does not inhibit the M1 alanyl aminopeptidase from Plasmodium falciparum
por: McGowan, Sheena
Publicado: (2013)