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Dissecting neural differentiation regulatory networks through epigenetic footprinting
Human pluripotent stem cell derived models that accurately recapitulate neural development in vitro and allow for the generation of specific neuronal subtypes are of major interest to the stem cell and biomedical community. Notch signaling, particularly through the Notch effector HES5, is a major pa...
Autores principales: | Ziller, Michael J., Edri, Reuven, Yaffe, Yakey, Donaghey, Julie, Pop, Ramona, Mallard, William, Issner, Robbyn, Gifford, Casey A., Goren, Alon, Xing, Jeff, Gu, Hongcang, Cachiarelli, Davide, Tsankov, Alexander, Epstein, Chuck, Rinn, John R., Mikkelsen, Tarjei S., Kohlbacher, Oliver, Gnirke, Andreas, Bernstein, Bradley E., Elkabetz, Yechiel, Meissner, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336237/ https://www.ncbi.nlm.nih.gov/pubmed/25533951 http://dx.doi.org/10.1038/nature13990 |
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