Treatment of diffuse alveolar hemorrhage secondary to lupus erythematosus with recombinant activated factor VII administered with a jet nebulizer

Diffuse alveolar hemorrhage (DAH) is a serious pulmonary complication in patients with autoimmune diseases who are undergoing chemotherapy or have had hematopoietic stem cell transplantation. The use of recombinant factor VIIa (rFVIIa) to treat the acute phase of DAH by endobronchial bronchoscopy ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Esper, Raúl Carrillo, Estrada, Isis Espinoza de los Monteros, de la Torre León, Teresa, Gutiérrez, Agustín Omar Rosales, López, Jorge Arturo Nava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336265/
https://www.ncbi.nlm.nih.gov/pubmed/25705408
http://dx.doi.org/10.1186/s40560-014-0047-2
_version_ 1782358438672596992
author Esper, Raúl Carrillo
Estrada, Isis Espinoza de los Monteros
de la Torre León, Teresa
Gutiérrez, Agustín Omar Rosales
López, Jorge Arturo Nava
author_facet Esper, Raúl Carrillo
Estrada, Isis Espinoza de los Monteros
de la Torre León, Teresa
Gutiérrez, Agustín Omar Rosales
López, Jorge Arturo Nava
author_sort Esper, Raúl Carrillo
collection PubMed
description Diffuse alveolar hemorrhage (DAH) is a serious pulmonary complication in patients with autoimmune diseases who are undergoing chemotherapy or have had hematopoietic stem cell transplantation. The use of recombinant factor VIIa (rFVIIa) to treat the acute phase of DAH by endobronchial bronchoscopy has been shown to have a significant clinical impact on the survival and evolution of these patients. We report a clinical case of a patient with DAH secondary to systemic lupus erythematosus (SLE) who was treated with rFVIIa administered using a jet nebulizer, obtaining an adequate hemostatic effect with immediate control of DAH and a significant improvement in gas exchange.
format Online
Article
Text
id pubmed-4336265
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-43362652015-02-22 Treatment of diffuse alveolar hemorrhage secondary to lupus erythematosus with recombinant activated factor VII administered with a jet nebulizer Esper, Raúl Carrillo Estrada, Isis Espinoza de los Monteros de la Torre León, Teresa Gutiérrez, Agustín Omar Rosales López, Jorge Arturo Nava J Intensive Care Case Report Diffuse alveolar hemorrhage (DAH) is a serious pulmonary complication in patients with autoimmune diseases who are undergoing chemotherapy or have had hematopoietic stem cell transplantation. The use of recombinant factor VIIa (rFVIIa) to treat the acute phase of DAH by endobronchial bronchoscopy has been shown to have a significant clinical impact on the survival and evolution of these patients. We report a clinical case of a patient with DAH secondary to systemic lupus erythematosus (SLE) who was treated with rFVIIa administered using a jet nebulizer, obtaining an adequate hemostatic effect with immediate control of DAH and a significant improvement in gas exchange. BioMed Central 2014-08-27 /pmc/articles/PMC4336265/ /pubmed/25705408 http://dx.doi.org/10.1186/s40560-014-0047-2 Text en © Esper et al.; licensee BioMed Central Ltd. 2014 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Esper, Raúl Carrillo
Estrada, Isis Espinoza de los Monteros
de la Torre León, Teresa
Gutiérrez, Agustín Omar Rosales
López, Jorge Arturo Nava
Treatment of diffuse alveolar hemorrhage secondary to lupus erythematosus with recombinant activated factor VII administered with a jet nebulizer
title Treatment of diffuse alveolar hemorrhage secondary to lupus erythematosus with recombinant activated factor VII administered with a jet nebulizer
title_full Treatment of diffuse alveolar hemorrhage secondary to lupus erythematosus with recombinant activated factor VII administered with a jet nebulizer
title_fullStr Treatment of diffuse alveolar hemorrhage secondary to lupus erythematosus with recombinant activated factor VII administered with a jet nebulizer
title_full_unstemmed Treatment of diffuse alveolar hemorrhage secondary to lupus erythematosus with recombinant activated factor VII administered with a jet nebulizer
title_short Treatment of diffuse alveolar hemorrhage secondary to lupus erythematosus with recombinant activated factor VII administered with a jet nebulizer
title_sort treatment of diffuse alveolar hemorrhage secondary to lupus erythematosus with recombinant activated factor vii administered with a jet nebulizer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336265/
https://www.ncbi.nlm.nih.gov/pubmed/25705408
http://dx.doi.org/10.1186/s40560-014-0047-2
work_keys_str_mv AT esperraulcarrillo treatmentofdiffusealveolarhemorrhagesecondarytolupuserythematosuswithrecombinantactivatedfactorviiadministeredwithajetnebulizer
AT estradaisisespinozadelosmonteros treatmentofdiffusealveolarhemorrhagesecondarytolupuserythematosuswithrecombinantactivatedfactorviiadministeredwithajetnebulizer
AT delatorreleonteresa treatmentofdiffusealveolarhemorrhagesecondarytolupuserythematosuswithrecombinantactivatedfactorviiadministeredwithajetnebulizer
AT gutierrezagustinomarrosales treatmentofdiffusealveolarhemorrhagesecondarytolupuserythematosuswithrecombinantactivatedfactorviiadministeredwithajetnebulizer
AT lopezjorgearturonava treatmentofdiffusealveolarhemorrhagesecondarytolupuserythematosuswithrecombinantactivatedfactorviiadministeredwithajetnebulizer

Ejemplares similares