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Efficacy of antithrombin in preclinical and clinical applications for sepsis-associated disseminated intravascular coagulation
Antithrombin (AT) is known as an important physiological anticoagulant. AT inactivates thrombin and multiple other coagulation factors, thereby strongly inhibiting the over-activation of the coagulation system during disseminated vascular coagulation (DIC). AT also suppresses the pro-inflammatory re...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336274/ https://www.ncbi.nlm.nih.gov/pubmed/25705422 http://dx.doi.org/10.1186/s40560-014-0051-6 |