The Polysaccharide Capsule of Streptococcus pneumonia Partially Impedes MyD88-Mediated Immunity during Pneumonia in Mice

Toll-like receptors (TLR) and the downstream adaptor protein MyD88 are considered crucial for protective immunity during bacterial infections. Streptococcus (S.) pneumoniae is a human respiratory pathogen and a large majority of clinical pneumococcal isolates expresses an external polysaccharide cap...

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Detalles Bibliográficos
Autores principales: de Vos, Alex F., Dessing, Mark C., Lammers, Adriana J. J., de Porto, Alexander P. N. A., Florquin, Sandrine, de Boer, Onno J., de Beer, Regina, Terpstra, Sanne, Bootsma, Hester J., Hermans, Peter W., van ‘t Veer, Cornelis, van der Poll, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336322/
https://www.ncbi.nlm.nih.gov/pubmed/25700108
http://dx.doi.org/10.1371/journal.pone.0118181

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