Cargando…
Comorbidity and Functional Trajectories From Midlife to Old Age: The Health and Retirement Study
BACKGROUND. The number of diseases and physical functioning difficulties tend to increase with age. The aim of this study was to examine the trajectories of physical functioning across age groups and whether the trajectories differ according to disease status in different population subgroups. METHO...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336333/ https://www.ncbi.nlm.nih.gov/pubmed/25060316 http://dx.doi.org/10.1093/gerona/glu113 |
_version_ | 1782358451704299520 |
---|---|
author | Stenholm, Sari Westerlund, Hugo Head, Jenny Hyde, Martin Kawachi, Ichiro Pentti, Jaana Kivimäki, Mika Vahtera, Jussi |
author_facet | Stenholm, Sari Westerlund, Hugo Head, Jenny Hyde, Martin Kawachi, Ichiro Pentti, Jaana Kivimäki, Mika Vahtera, Jussi |
author_sort | Stenholm, Sari |
collection | PubMed |
description | BACKGROUND. The number of diseases and physical functioning difficulties tend to increase with age. The aim of this study was to examine the trajectories of physical functioning across age groups and whether the trajectories differ according to disease status in different population subgroups. METHODS. Repeat data from a nationally representative population sample, the Health and Retirement Study, was used. Participants were 10,709 men and 13,477 women aged 60–107 years at baseline with biennial surveys from 1992 to 2010. Average length of follow-up was 10.3 years ranging from 0 to 18 years. Disease status and physical functioning was asked about at all study phases and 10 items were summed to obtain a physical functioning score (0–10). RESULTS. Age modified the relationship between number of chronic diseases and physical functioning with older participants having more physical functioning difficulties with increasing number of diseases. An average 70-year-old participant with no diseases had 0.89 (95% CI: 0.85–0.93) physical functioning difficulties, with one disease 1.72 (95% CI: 1.69–1.76) difficulties, with two diseases 2.57 (95% CI: 2.52–2.62) difficulties, and with three or more diseases 3.82 (95% CI: 3.76–3.88) difficulties. Of the individual diseases memory-related diseases, stroke, pulmonary diseases, and arthritis were associated with significantly higher physical functioning difficulties compared with other diseases. CONCLUSIONS. Comorbidity is associated with greater burden of physical functioning difficulties. Of the studied diseases, memory-related diseases, stroke, pulmonary diseases, and arthritis alone or in combination limit most physical functioning. |
format | Online Article Text |
id | pubmed-4336333 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-43363332015-03-02 Comorbidity and Functional Trajectories From Midlife to Old Age: The Health and Retirement Study Stenholm, Sari Westerlund, Hugo Head, Jenny Hyde, Martin Kawachi, Ichiro Pentti, Jaana Kivimäki, Mika Vahtera, Jussi J Gerontol A Biol Sci Med Sci Research Article BACKGROUND. The number of diseases and physical functioning difficulties tend to increase with age. The aim of this study was to examine the trajectories of physical functioning across age groups and whether the trajectories differ according to disease status in different population subgroups. METHODS. Repeat data from a nationally representative population sample, the Health and Retirement Study, was used. Participants were 10,709 men and 13,477 women aged 60–107 years at baseline with biennial surveys from 1992 to 2010. Average length of follow-up was 10.3 years ranging from 0 to 18 years. Disease status and physical functioning was asked about at all study phases and 10 items were summed to obtain a physical functioning score (0–10). RESULTS. Age modified the relationship between number of chronic diseases and physical functioning with older participants having more physical functioning difficulties with increasing number of diseases. An average 70-year-old participant with no diseases had 0.89 (95% CI: 0.85–0.93) physical functioning difficulties, with one disease 1.72 (95% CI: 1.69–1.76) difficulties, with two diseases 2.57 (95% CI: 2.52–2.62) difficulties, and with three or more diseases 3.82 (95% CI: 3.76–3.88) difficulties. Of the individual diseases memory-related diseases, stroke, pulmonary diseases, and arthritis were associated with significantly higher physical functioning difficulties compared with other diseases. CONCLUSIONS. Comorbidity is associated with greater burden of physical functioning difficulties. Of the studied diseases, memory-related diseases, stroke, pulmonary diseases, and arthritis alone or in combination limit most physical functioning. Oxford University Press 2015-03 2014-07-24 /pmc/articles/PMC4336333/ /pubmed/25060316 http://dx.doi.org/10.1093/gerona/glu113 Text en © The Author 2014. Published by Oxford University Press on behalf of The Gerontological Society of America. http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Stenholm, Sari Westerlund, Hugo Head, Jenny Hyde, Martin Kawachi, Ichiro Pentti, Jaana Kivimäki, Mika Vahtera, Jussi Comorbidity and Functional Trajectories From Midlife to Old Age: The Health and Retirement Study |
title | Comorbidity and Functional Trajectories From Midlife to Old Age: The Health and Retirement Study |
title_full | Comorbidity and Functional Trajectories From Midlife to Old Age: The Health and Retirement Study |
title_fullStr | Comorbidity and Functional Trajectories From Midlife to Old Age: The Health and Retirement Study |
title_full_unstemmed | Comorbidity and Functional Trajectories From Midlife to Old Age: The Health and Retirement Study |
title_short | Comorbidity and Functional Trajectories From Midlife to Old Age: The Health and Retirement Study |
title_sort | comorbidity and functional trajectories from midlife to old age: the health and retirement study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336333/ https://www.ncbi.nlm.nih.gov/pubmed/25060316 http://dx.doi.org/10.1093/gerona/glu113 |
work_keys_str_mv | AT stenholmsari comorbidityandfunctionaltrajectoriesfrommidlifetooldagethehealthandretirementstudy AT westerlundhugo comorbidityandfunctionaltrajectoriesfrommidlifetooldagethehealthandretirementstudy AT headjenny comorbidityandfunctionaltrajectoriesfrommidlifetooldagethehealthandretirementstudy AT hydemartin comorbidityandfunctionaltrajectoriesfrommidlifetooldagethehealthandretirementstudy AT kawachiichiro comorbidityandfunctionaltrajectoriesfrommidlifetooldagethehealthandretirementstudy AT penttijaana comorbidityandfunctionaltrajectoriesfrommidlifetooldagethehealthandretirementstudy AT kivimakimika comorbidityandfunctionaltrajectoriesfrommidlifetooldagethehealthandretirementstudy AT vahterajussi comorbidityandfunctionaltrajectoriesfrommidlifetooldagethehealthandretirementstudy |