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Anti-tumor necrosis factor patent expiration and the risks of biocopies in clinical practice

Biosimilars that were not compared in clinical trials with the compound innovator are not true biosimilars (biocopies) and are associated with risks that the clinical rheumatologist should be aware of before generalized use. This article comments on various aspects surrounding the use of such biocop...

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Detalles Bibliográficos
Autores principales: Scheinberg, Morton, Castañeda-Hernández, Gilberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336503/
https://www.ncbi.nlm.nih.gov/pubmed/25677586
http://dx.doi.org/10.1186/s13075-014-0501-5
Descripción
Sumario:Biosimilars that were not compared in clinical trials with the compound innovator are not true biosimilars (biocopies) and are associated with risks that the clinical rheumatologist should be aware of before generalized use. This article comments on various aspects surrounding the use of such biocopies in clinical rheumatology.