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Fate by RNA methylation: m(6)A steers stem cell pluripotency
The N(6)-methyladenosine (m(6)A) modification of mRNA has a crucial function in regulating pluripotency in murine stem cells: it facilitates resolution of naïve pluripotency towards differentiation.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336730/ https://www.ncbi.nlm.nih.gov/pubmed/25723450 http://dx.doi.org/10.1186/s13059-015-0609-1 |
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| author | Zhao, Boxuan Simen He, Chuan |
| author_facet | Zhao, Boxuan Simen He, Chuan |
| author_sort | Zhao, Boxuan Simen |
| collection | PubMed |
| description | The N(6)-methyladenosine (m(6)A) modification of mRNA has a crucial function in regulating pluripotency in murine stem cells: it facilitates resolution of naïve pluripotency towards differentiation. |
| format | Online Article Text |
| id | pubmed-4336730 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2015 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-43367302015-02-23 Fate by RNA methylation: m(6)A steers stem cell pluripotency Zhao, Boxuan Simen He, Chuan Genome Biol Research Highlight The N(6)-methyladenosine (m(6)A) modification of mRNA has a crucial function in regulating pluripotency in murine stem cells: it facilitates resolution of naïve pluripotency towards differentiation. BioMed Central 2015-02-22 2015 /pmc/articles/PMC4336730/ /pubmed/25723450 http://dx.doi.org/10.1186/s13059-015-0609-1 Text en © Zhao and He; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| spellingShingle | Research Highlight Zhao, Boxuan Simen He, Chuan Fate by RNA methylation: m(6)A steers stem cell pluripotency |
| title | Fate by RNA methylation: m(6)A steers stem cell pluripotency |
| title_full | Fate by RNA methylation: m(6)A steers stem cell pluripotency |
| title_fullStr | Fate by RNA methylation: m(6)A steers stem cell pluripotency |
| title_full_unstemmed | Fate by RNA methylation: m(6)A steers stem cell pluripotency |
| title_short | Fate by RNA methylation: m(6)A steers stem cell pluripotency |
| title_sort | fate by rna methylation: m(6)a steers stem cell pluripotency |
| topic | Research Highlight |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336730/ https://www.ncbi.nlm.nih.gov/pubmed/25723450 http://dx.doi.org/10.1186/s13059-015-0609-1 |
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