Chorea Associated with High Titers of Antiphospholipid Antibodies in the Absence of Antiphospholipid Antibody Syndrome

BACKGROUND: Chorea associated with high titers of antiphospholipid antibodies in the absence of antiphospholipid antibody syndrome has been seldom reported. CASE REPORT: An 89-year-old female developed persistent right side chorea associated with high titers of anticardiolipin antibody (antiphosphol...

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Autores principales: Safarpour, Damoun, Buckingham, Sarah, Jabbari, Bahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Columbia University Libraries/Information Services 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336732/
https://www.ncbi.nlm.nih.gov/pubmed/25774325
http://dx.doi.org/10.7916/D8DB80M9
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author Safarpour, Damoun
Buckingham, Sarah
Jabbari, Bahman
author_facet Safarpour, Damoun
Buckingham, Sarah
Jabbari, Bahman
author_sort Safarpour, Damoun
collection PubMed
description BACKGROUND: Chorea associated with high titers of antiphospholipid antibodies in the absence of antiphospholipid antibody syndrome has been seldom reported. CASE REPORT: An 89-year-old female developed persistent right side chorea associated with high titers of anticardiolipin antibody (antiphospholipid antibosies immunoglobulin (Ig)M, 45 MPL and 112 IgM aCL (MPL) after 3 months) but normal lupus anticoagulants. Her magnetic resonance imaging (MRI) showed no abnormality, but positron emission tomography (PET) demonstrated increased bilateral striatal metabolic activity, more on the left side. Her MRI showed no cause for chorea. The PET scan demonstrated a marked increase in the metabolic activity of the left basal ganglia. DISCUSSION: Her chorea remained unchanged over a 9-month follow-up period. The literature on chorea associated with high titers of antiphospholipid antibodies in the absence of antiphospholipid syndrome is reviewed.
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spelling pubmed-43367322015-03-13 Chorea Associated with High Titers of Antiphospholipid Antibodies in the Absence of Antiphospholipid Antibody Syndrome Safarpour, Damoun Buckingham, Sarah Jabbari, Bahman Tremor Other Hyperkinet Mov (N Y) Case Reports BACKGROUND: Chorea associated with high titers of antiphospholipid antibodies in the absence of antiphospholipid antibody syndrome has been seldom reported. CASE REPORT: An 89-year-old female developed persistent right side chorea associated with high titers of anticardiolipin antibody (antiphospholipid antibosies immunoglobulin (Ig)M, 45 MPL and 112 IgM aCL (MPL) after 3 months) but normal lupus anticoagulants. Her magnetic resonance imaging (MRI) showed no abnormality, but positron emission tomography (PET) demonstrated increased bilateral striatal metabolic activity, more on the left side. Her MRI showed no cause for chorea. The PET scan demonstrated a marked increase in the metabolic activity of the left basal ganglia. DISCUSSION: Her chorea remained unchanged over a 9-month follow-up period. The literature on chorea associated with high titers of antiphospholipid antibodies in the absence of antiphospholipid syndrome is reviewed. Columbia University Libraries/Information Services 2015-02-13 /pmc/articles/PMC4336732/ /pubmed/25774325 http://dx.doi.org/10.7916/D8DB80M9 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution–Noncommerical–No Derivatives License, which permits the user to copy, distribute, and transmit the work provided that the original author and source are credited; that no commercial use is made of the work; and that the work is not altered or transformed.
spellingShingle Case Reports
Safarpour, Damoun
Buckingham, Sarah
Jabbari, Bahman
Chorea Associated with High Titers of Antiphospholipid Antibodies in the Absence of Antiphospholipid Antibody Syndrome
title Chorea Associated with High Titers of Antiphospholipid Antibodies in the Absence of Antiphospholipid Antibody Syndrome
title_full Chorea Associated with High Titers of Antiphospholipid Antibodies in the Absence of Antiphospholipid Antibody Syndrome
title_fullStr Chorea Associated with High Titers of Antiphospholipid Antibodies in the Absence of Antiphospholipid Antibody Syndrome
title_full_unstemmed Chorea Associated with High Titers of Antiphospholipid Antibodies in the Absence of Antiphospholipid Antibody Syndrome
title_short Chorea Associated with High Titers of Antiphospholipid Antibodies in the Absence of Antiphospholipid Antibody Syndrome
title_sort chorea associated with high titers of antiphospholipid antibodies in the absence of antiphospholipid antibody syndrome
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336732/
https://www.ncbi.nlm.nih.gov/pubmed/25774325
http://dx.doi.org/10.7916/D8DB80M9
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