MiR-27a ameliorates inflammatory damage to the blood-spinal cord barrier after spinal cord ischemia: reperfusion injury in rats by downregulating TICAM-2 of the TLR(4) signaling pathway

BACKGROUND: Spinal cord ischemia reperfusion (IR) injury causes inflammation and subsequently increases blood-spinal cord barrier leakage and Toll-like receptor 4 (TLR(4)) pathway activation. MicroRNAs (miRs) effectively regulate numerous target mRNAs during ischemia. However, their roles during IR...

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Detalles Bibliográficos
Autores principales: Li, Xiao-Qian, Lv, Huang-Wei, Wang, Zhi-Lin, Tan, Wen-Fei, Fang, Bo, Ma, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336736/
https://www.ncbi.nlm.nih.gov/pubmed/25876455
http://dx.doi.org/10.1186/s12974-015-0246-3

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