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Improved production of sublancin via introduction of three characteristic promoters into operon clusters responsible for this novel distinct glycopeptide biosynthesis

BACKGROUND: Sublancin is a novel and distinct antimicrobial glycopeptide that can be used as an alternative to conventional antibiotics. The reported production of sublancin by Bacillus subtilis 168 is poor because transcriptional regulatory circuit of sunA, a gene that encodes presublancin, is comp...

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Detalles Bibliográficos
Autores principales: Ji, Shengyue, Li, Weili, Baloch, Abdul Rasheed, Wang, Meng, Cao, Binyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336743/
https://www.ncbi.nlm.nih.gov/pubmed/25879813
http://dx.doi.org/10.1186/s12934-015-0201-0

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