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Structure of human cytoplasmic dynein-2 primed for its powerstroke
Members of the dynein family, consisting of cytoplasmic and axonemal isoforms, are motors that move towards the minus ends of microtubules. Cytoplasmic dynein-1 (dynein-1) plays roles in mitosis and cellular cargo transport(1), and is implicated in viral infections(2) and neurodegenerative diseases(...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336856/ https://www.ncbi.nlm.nih.gov/pubmed/25470043 http://dx.doi.org/10.1038/nature14023 |