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Effect of the DGAT1 inhibitor pradigastat on triglyceride and apoB48 levels in patients with familial chylomicronemia syndrome

BACKGROUND: Familial chylomicronemia syndrome (FCS) is a rare lipid disease caused by complete lipoprotein lipase (LPL) deficiency resulting in fasting chylomicronemia and severe hypertriglyceridemia. Inhibition of diacylglycerol acyltransferase 1 (DGAT1), which mediates chylomicron triglyceride (TG...

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Detalles Bibliográficos
Autores principales:	Meyers, Charles Daniel, Tremblay, Karine, Amer, Ahmed, Chen, Jin, Jiang, Liewen, Gaudet, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337059/ https://www.ncbi.nlm.nih.gov/pubmed/25889044 http://dx.doi.org/10.1186/s12944-015-0006-5

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