Cargando…

Functional magnetic resonance imaging in oncology: state of the art

In the investigation of tumors with conventional magnetic resonance imaging, both quantitative characteristics, such as size, edema, necrosis, and presence of metastases, and qualitative characteristics, such as contrast enhancement degree, are taken into consideration. However, changes in cell meta...

Descripción completa

Detalles Bibliográficos
Autores principales: Guimaraes, Marcos Duarte, Schuch, Alice, Hochhegger, Bruno, Gross, Jefferson Luiz, Chojniak, Rubens, Marchiori, Edson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Radiologia e Diagnóstico por Imagem 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337156/
https://www.ncbi.nlm.nih.gov/pubmed/25741058
http://dx.doi.org/10.1590/S0100-39842014000200013
_version_ 1782358571287052288
author Guimaraes, Marcos Duarte
Schuch, Alice
Hochhegger, Bruno
Gross, Jefferson Luiz
Chojniak, Rubens
Marchiori, Edson
author_facet Guimaraes, Marcos Duarte
Schuch, Alice
Hochhegger, Bruno
Gross, Jefferson Luiz
Chojniak, Rubens
Marchiori, Edson
author_sort Guimaraes, Marcos Duarte
collection PubMed
description In the investigation of tumors with conventional magnetic resonance imaging, both quantitative characteristics, such as size, edema, necrosis, and presence of metastases, and qualitative characteristics, such as contrast enhancement degree, are taken into consideration. However, changes in cell metabolism and tissue physiology which precede morphological changes cannot be detected by the conventional technique. The development of new magnetic resonance imaging techniques has enabled the functional assessment of the structures in order to obtain information on the different physiological processes of the tumor microenvironment, such as oxygenation levels, cellularity and vascularity. The detailed morphological study in association with the new functional imaging techniques allows for an appropriate approach to cancer patients, including the phases of diagnosis, staging, response evaluation and follow-up, with a positive impact on their quality of life and survival rate.
format Online
Article
Text
id pubmed-4337156
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Colégio Brasileiro de Radiologia e Diagnóstico por Imagem
record_format MEDLINE/PubMed
spelling pubmed-43371562015-03-04 Functional magnetic resonance imaging in oncology: state of the art Guimaraes, Marcos Duarte Schuch, Alice Hochhegger, Bruno Gross, Jefferson Luiz Chojniak, Rubens Marchiori, Edson Radiol Bras Review Article In the investigation of tumors with conventional magnetic resonance imaging, both quantitative characteristics, such as size, edema, necrosis, and presence of metastases, and qualitative characteristics, such as contrast enhancement degree, are taken into consideration. However, changes in cell metabolism and tissue physiology which precede morphological changes cannot be detected by the conventional technique. The development of new magnetic resonance imaging techniques has enabled the functional assessment of the structures in order to obtain information on the different physiological processes of the tumor microenvironment, such as oxygenation levels, cellularity and vascularity. The detailed morphological study in association with the new functional imaging techniques allows for an appropriate approach to cancer patients, including the phases of diagnosis, staging, response evaluation and follow-up, with a positive impact on their quality of life and survival rate. Colégio Brasileiro de Radiologia e Diagnóstico por Imagem 2014 /pmc/articles/PMC4337156/ /pubmed/25741058 http://dx.doi.org/10.1590/S0100-39842014000200013 Text en © Colégio Brasileiro de Radiologia e Diagnóstico por Imagem http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Guimaraes, Marcos Duarte
Schuch, Alice
Hochhegger, Bruno
Gross, Jefferson Luiz
Chojniak, Rubens
Marchiori, Edson
Functional magnetic resonance imaging in oncology: state of the art
title Functional magnetic resonance imaging in oncology: state of the art
title_full Functional magnetic resonance imaging in oncology: state of the art
title_fullStr Functional magnetic resonance imaging in oncology: state of the art
title_full_unstemmed Functional magnetic resonance imaging in oncology: state of the art
title_short Functional magnetic resonance imaging in oncology: state of the art
title_sort functional magnetic resonance imaging in oncology: state of the art
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337156/
https://www.ncbi.nlm.nih.gov/pubmed/25741058
http://dx.doi.org/10.1590/S0100-39842014000200013
work_keys_str_mv AT guimaraesmarcosduarte functionalmagneticresonanceimaginginoncologystateoftheart
AT schuchalice functionalmagneticresonanceimaginginoncologystateoftheart
AT hochheggerbruno functionalmagneticresonanceimaginginoncologystateoftheart
AT grossjeffersonluiz functionalmagneticresonanceimaginginoncologystateoftheart
AT chojniakrubens functionalmagneticresonanceimaginginoncologystateoftheart
AT marchioriedson functionalmagneticresonanceimaginginoncologystateoftheart