Toll-like receptor 4 inhibition within the paraventricular nucleus attenuates blood pressure and inflammatory response in a genetic model of hypertension

BACKGROUND: Despite the availability of several antihypertensive medications, the morbidity and mortality caused by hypertension is on the rise, suggesting the need for investigation of novel signaling pathways involved in its pathogenesis. Recent evidence suggests the role of toll-like receptor (TL...

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Detalles Bibliográficos
Autores principales: Dange, Rahul B, Agarwal, Deepmala, Teruyama, Ryoichi, Francis, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337244/
https://www.ncbi.nlm.nih.gov/pubmed/25879545
http://dx.doi.org/10.1186/s12974-015-0242-7

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