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Using a Systems Pharmacology Approach to Study the Effect of Statins on the Early Stage of Atherosclerosis in Humans

More than 100,000 people have participated in controlled trials of statins (lowering cholesterol drugs) since the introduction of lovastatin in the 1980s. Meta-analyses of this data have shown that statins have a beneficial effect on treated groups compared to control groups, reducing cardiovascular...

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Detalles Bibliográficos
Autores principales: Pichardo–Almarza, C, Metcalf, L, Finkelstein, A, Diaz-Zuccarini, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337252/
https://www.ncbi.nlm.nih.gov/pubmed/26225221
http://dx.doi.org/10.1002/psp4.7