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Shikonin Induces Apoptosis, Necrosis, and Premature Senescence of Human A549 Lung Cancer Cells through Upregulation of p53 Expression

Shikonin, a natural naphthoquinone pigment isolated from Lithospermum erythrorhizon, has been reported to suppress growth of various cancer cells. This study was aimed to investigate whether this chemical could also inhibit cell growth of lung cancer cells and, if so, works via what molecular mechan...

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Detalles Bibliográficos
Autores principales:	Yeh, Yueh-Chiao, Liu, Tsun-Jui, Lai, Hui-Chin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337265/ https://www.ncbi.nlm.nih.gov/pubmed/25737737 http://dx.doi.org/10.1155/2015/620383

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