Cargando…

Lipid Peroxidation-Mediated Inflammation Promotes Cell Apoptosis through Activation of NF-κB Pathway in Rheumatoid Arthritis Synovial Cells

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of multiple joints. The central pathogenesis of RA is the proliferation of synovial fibroblasts in response to inflammatory cytokines. However, some of the targeted therapies for inflammation reactions d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yin, Geng, Wang, Ying, Cen, Xiao-min, Yang, Min, Liang, Yan, Xie, Qi-bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337269/ https://www.ncbi.nlm.nih.gov/pubmed/25741130 http://dx.doi.org/10.1155/2015/460310

Ejemplares similares

Pim-2/mTORC1 Pathway Shapes Inflammatory Capacity in Rheumatoid Arthritis Synovial Cells Exposed to Lipid Peroxidations
por: Yin, Geng, et al.
Publicado: (2015)

Inhibition of NF-κB signaling pathway induces apoptosis and suppresses proliferation and angiogenesis of human fibroblast-like synovial cells in rheumatoid arthritis
por: Xia, Zhong-Bin, et al.
Publicado: (2018)

Cell biology of synovial inflammation and secondary osteoporosis in rheumatoid arthritis
por: Tanaka, Y, et al.
Publicado: (2003)

CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts
por: Zhai, Yue, et al.
Publicado: (2015)

Monocytes are essential for inhibition of synovial T-cell glucocorticoid-mediated apoptosis in rheumatoid arthritis
por: Makrygiannakis, Dimitrios, et al.
Publicado: (2008)

Cells of the synovium in rheumatoid arthritis. Synovial fibroblasts
por: Müller-Ladner, Ulf, et al.
Publicado: (2007)

The Impact of Synovial NF-κB Activation on Apoptosis Pattern Change During Adjuvant-induced Inflammation
por: Golabi, Sahar, et al.
Publicado: (2017)

Additive Effects of VDBP and 1,25(OH)2D3 on the Viability and Apoptosis of Rheumatoid Arthritis Synovial Fibroblasts
por: Zhang, Yeyong, et al.
Publicado: (2021)

Variability in synovial inflammation in rheumatoid arthritis investigated by microarray technology
por: Lindberg, Johan, et al.
Publicado: (2006)

Chemokine blockade in patients with rheumatoid arthritis: reduction of synovial inflammation
por: Haringman, JJ, et al.
Publicado: (2002)

Rheumatoid Arthritis Synovial Inflammation Quantification Using Computer Vision
por: Guan, Steven, et al.
Publicado: (2022)

Adipokines and Inflammation Alter the Interaction Between Rheumatoid Arthritis Synovial Fibroblasts and Endothelial Cells
por: Hasseli, Rebecca, et al.
Publicado: (2020)

Piceatannol suppresses inflammation and promotes apoptosis in rheumatoid arthritis-fibroblast-like synoviocytes by inhibiting the NF-κB and MAPK signaling pathways
por: Gao, Xuezhong, et al.
Publicado: (2022)

MiR-125a-3p inhibits cell proliferation and inflammation responses in fibroblast-like synovial cells in rheumatoid arthritis by mediating the Wnt/β-catenin and NF-κB pathways via targeting MAST3
por: Wang, Yingxue, et al.
Publicado: (2021)

Apoptosis is not the major death mechanism induced by celecoxib on rheumatoid arthritis synovial fibroblasts
por: Audo, Rachel, et al.
Publicado: (2007)

Synovial fluid leukocyte apoptosis is inhibited in patients with very early rheumatoid arthritis
por: Raza, Karim, et al.
Publicado: (2006)

Mechanisms of resistance against Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts
por: Pap, T, et al.
Publicado: (2003)

AKT regulates TNF-alpha-mediated apoptosis of rheumatoid arthritis synovial fibroblasts
por: Mountz, JD, et al.
Publicado: (2001)

Endogenous Galectin-9 Suppresses Apoptosis in Human Rheumatoid Arthritis Synovial Fibroblasts
por: Pearson, Mark J., et al.
Publicado: (2018)

Synovial Histopathology in Early Rheumatoid Arthritis
por: Hirohata, Shunsei, et al.
Publicado: (2000)

Activation of Synovial Fibroblasts in Rheumatoid Arthritis
por: Gay, Steffen, et al.
Publicado: (2000)

Synovial fluid proteome in rheumatoid arthritis
por: Bhattacharjee, Mitali, et al.
Publicado: (2016)

Susceptibility of rheumatoid arthritis synovial fibroblasts to FasL- and TRAIL-induced apoptosis is cell cycle-dependent
por: Pundt, Noreen, et al.
Publicado: (2009)

Hypoxia upregulates angiogenesis and synovial cell migration in rheumatoid arthritis
por: Akhavani, Mohammed A, et al.
Publicado: (2009)

Redox Balance Alterations and Hyporesponsiveness of Synovial T Cells in Rheumatoid Arthritis
por: Breedveld, Ferdinand C, et al.
Publicado: (2000)

Overexpression of IκBα in cardiomyocytes alleviates hydrogen peroxide-induced apoptosis and autophagy by inhibiting NF-κB activation
por: Han, Min, et al.
Publicado: (2020)

Differential effects of T-cell specific PKC-theta inhibition or selective intra-articular NF-κB inhibition on synovial inflammation in rat adjuvant arthritis
por: Tas, SW, et al.
Publicado: (2005)

Interleukin-29 modulates proinflammatory cytokine production in synovial inflammation of rheumatoid arthritis
por: Wang, Fang, et al.
Publicado: (2012)

Machine learning identification of thresholds to discriminate osteoarthritis and rheumatoid arthritis synovial inflammation
por: Mehta, Bella, et al.
Publicado: (2023)

Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis
por: Shi, Qin, et al.
Publicado: (2012)

Arachidonic acid-regulated calcium signaling in T cells from patients with rheumatoid arthritis promotes synovial inflammation
por: Ye, Zhongde, et al.
Publicado: (2021)

Preferential expression of NF-κB-inducing kinase (NIK) in blood vessels of rheumatoid arthritis synovial tissue containing ectopic lymphoid neogenesis
por: Noort, A R, et al.
Publicado: (2010)

Synovial fibroblast‐targeting liposomes encapsulating an NF‐κB‐blocking peptide ameliorates zymosan‐induced synovial inflammation
por: You, Changcheng, et al.
Publicado: (2018)

Regulation of NF-κB-Induced Inflammatory Signaling by Lipid Peroxidation-Derived Aldehydes
por: Yadav, Umesh C. S., et al.
Publicado: (2013)

Non-canonical NF-κB signaling in endothelial cells may enhance synovial inflammation by stimulating angiogenesis
por: Noort, Ae-Ri, et al.
Publicado: (2011)

Mir204 and Mir211 suppress synovial inflammation and proliferation in rheumatoid arthritis by targeting Ssrp1
por: Wang, Qi-Shan, et al.
Publicado: (2022)

Association between Serum 25-Hydroxyvitamin D Level and Rheumatoid Arthritis
por: Cen, Xiaomin, et al.
Publicado: (2015)

Immune cell - derived microparticles contribute to the resistance of rheumatoid arthritis synovial fibroblasts to death receptor-mediated apoptosis
por: Frank, Mojca, et al.
Publicado: (2012)

Activation of inflammation and resolution pathways of lipid mediators in synovial fluid from patients with severe rheumatoid arthritis compared with severe osteoarthritis
por: Sano, Yutaka, et al.
Publicado: (2020)

Screening and identification of potential hub genes and immune cell infiltration in the synovial tissue of rheumatoid arthritis by bioinformatic approach
por: Feng, Zhi-wei, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_p35i5ltabf9cjscqp0mubm48vm