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Generation of a Retinoblastoma (Rb)1-inducible dominant-negative (DN) mouse model
Retinoblastoma 1 (Rb1) is an essential gene regulating cellular proliferation, differentiation, and homeostasis. To exert these functions, Rb1 is recruited and physically interacts with a growing variety of signaling pathways. While Rb1 does not appear to be ubiquitously expressed, its expression ha...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337335/ https://www.ncbi.nlm.nih.gov/pubmed/25755634 http://dx.doi.org/10.3389/fncel.2015.00052 |