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Induction of Tet3-dependent Epigenetic Remodeling by Low-dose Hydralazine Attenuates Progression of Chronic Kidney Disease

Progression of chronic kidney disease remains a principal problem in clinical nephrology and there is a pressing need for novel therapeutics and biomarkers. Aberrant promoter CpG island methylation and subsequent transcriptional silencing of specific genes have emerged as contributors to progression...

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Detalles Bibliográficos
Autores principales:	Tampe, Björn, Tampe, Desiree, Zeisberg, Elisabeth M., Müller, Gerhard A., Bechtel-Walz, Wibke, Koziolek, Michael, Kalluri, Raghu, Zeisberg, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337426/ https://www.ncbi.nlm.nih.gov/pubmed/25717475 http://dx.doi.org/10.1016/j.ebiom.2014.11.005

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