Cargando…

A novel long non-coding RNA, hypoxia-inducible factor-2α promoter upstream transcript, functions as an inhibitor of osteosarcoma stem cells in vitro

Long non-coding RNAs (lncRNAs) have recently been identified as novel modulators of malignant tumors. However, the function of lncRNAs in cancer stem cells (CSCs) remains to be elucidated. The present study aimed to investigate the regulating role of a novel lncRNA, hypoxia-inducible factor-2α (HIF-...

Descripción completa

Detalles Bibliográficos
Autores principales:	WANG, YONGCHENG, YAO, JIE, MENG, HAOYE, YU, ZHIGUO, WANG, ZHIGANG, YUAN, XUELING, CHEN, HONG, WANG, AIYUAN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337490/ https://www.ncbi.nlm.nih.gov/pubmed/25434862 http://dx.doi.org/10.3892/mmr.2014.3024

Ejemplares similares

Fabrication and in vitro evaluation of an articular cartilage extracellular matrix-hydroxyapatite bilayered scaffold with low permeability for interface tissue engineering
por: Wang, Yongcheng, et al.
Publicado: (2014)

Diffusion of neutral solutes within human osteoarthritic cartilage: Effect of loading patterns
por: Meng, Haoye, et al.
Publicado: (2019)

ETC-159, an Upstream Wnt inhibitor, Induces Tumour Necrosis via Modulation of Angiogenesis in Osteosarcoma
por: Chua, Kenon, et al.
Publicado: (2023)

An updated meta-analysis of the asporin gene D-repeat in knee osteoarthritis: effects of gender and ethnicity
por: Liu, Ruoxi, et al.
Publicado: (2017)

Translation of the human erythropoietin transcript is regulated by an upstream open reading frame in response to hypoxia
por: Barbosa, Cristina, et al.
Publicado: (2014)

Icariin activates far upstream element binding protein 1 to regulate hypoxia-inducible factor-1α and hypoxia-inducible factor-2α signaling and benefits chondrocytes
por: Wang, Pengzhen, et al.
Publicado: (2023)

Mesenchymal Stem Cell Migration and Proliferation Are Mediated by Hypoxia-Inducible Factor-1α Upstream of Notch and SUMO Pathways
por: Ciria, María, et al.
Publicado: (2017)

Therapeutic effect of human umbilical cord mesenchymal stem cells in early traumatic osteonecrosis of the femoral head
por: Zhao, Jun, et al.
Publicado: (2022)

Hypoxia increases the expression of stem cell markers in human osteosarcoma cells
por: Lin, Jinluan, et al.
Publicado: (2021)

Far upstream element‐binding protein 1 confers lobaplatin resistance by transcriptionally activating PTGES and facilitating the arachidonic acid metabolic pathway in osteosarcoma
por: Ma, Qiong, et al.
Publicado: (2023)

Analysis of early stage osteonecrosis of the human femoral head and the mechanism of femoral head collapse
por: Wang, Cheng, et al.
Publicado: (2018)

Diagnosis and treatment of traumatic vascular injury of limbs in military and emergency medicine: A systematic review
por: Xu, Yichi, et al.
Publicado: (2019)

The Regulation of Xylem Development by Transcription Factors and Their Upstream MicroRNAs
por: Sun, Pengfang, et al.
Publicado: (2022)

Recognize the role of CD146/MCAM in the osteosarcoma progression: an in vitro study
por: Lei, Xing, et al.
Publicado: (2021)

Long non-coding RNAs in osteosarcoma
por: Chen, Ruiling, et al.
Publicado: (2017)

Potential and recent advances of microcarriers in repairing cartilage defects()
por: Liao, Sida, et al.
Publicado: (2021)

Long noncoding RNA ANRIL is activated by hypoxia-inducible factor-1α and promotes osteosarcoma cell invasion and suppresses cell apoptosis upon hypoxia
por: Wei, Xiaokang, et al.
Publicado: (2016)

Is ABA the earliest upstream inhibitor of apical dominance?
por: Nguyen, Thien Q., et al.
Publicado: (2017)

The optimal time to inject bone mesenchymal stem cells for fracture healing in a murine model
por: Wang, Xin, et al.
Publicado: (2018)

Mediator Acts Upstream of the Transcriptional Activator Gal4
por: Ang, Keven, et al.
Publicado: (2012)

Hypoxia-induced autophagy as an additional mechanism in human osteosarcoma radioresistance
por: Feng, Helin, et al.
Publicado: (2016)

Expression of the Mouse Pre-T Cell Receptor α Gene Is Controlled by an Upstream Region Containing a Transcriptional Enhancer
por: Reizis, Boris, et al.
Publicado: (1999)

Upstream
por: Evans, Virginia, 1945-
Publicado: (2005)

Upstream
por: Evans, Virginia, 1945-
Publicado: (2005)

Retraction Note: Long noncoding RNA ANRIL is activated by hypoxia-inducible factor-1α and promotes osteosarcoma cell invasion and suppresses cell apoptosis upon hypoxia
por: Wei, Xiaokang, et al.
Publicado: (2017)

Quantifying the degradation of degradable implants and bone formation in the femoral condyle using micro-CT 3D reconstruction
por: Xu, Yichi, et al.
Publicado: (2018)

AAV-Anti-miR-214 Prevents Collapse of the Femoral Head in Osteonecrosis by Regulating Osteoblast and Osteoclast Activities
por: Wang, Cheng, et al.
Publicado: (2019)

Upstream Tracker Upgrade Status of the Upstream Tracker
por: Andreou, Dimitra
Publicado: (2022)

LHCb Upstream Tracker Upgrade
por: Wang, Jianchun
Publicado: (2015)

MicroRNA-33b Inhibits the Proliferation and Migration of Osteosarcoma Cells via Targeting Hypoxia-Inducible Factor-1α
por: Zhou, Yong, et al.
Publicado: (2017)

Roxarsone Promotes Glycolysis and Angiogenesis by Inducing Hypoxia-Inducible Factor-1α In Vitro and In Vivo
por: Chen, Xin, et al.
Publicado: (2021)

Patterns of variation in DNA segments upstream of transcription start sites
por: Labuda, Damian, et al.
Publicado: (2007)

Local potentiation of stress-responsive genes by upstream noncoding transcription
por: Takemata, Naomichi, et al.
Publicado: (2016)

Selective Constraint on the Upstream Open Reading Frames That Overlap with Coding Sequences in Animals
por: Hsu, Ming-Kung, et al.
Publicado: (2012)

Exploration of various roles of hypoxia genes in osteosarcoma
por: Ma, Jimin, et al.
Publicado: (2022)

Construction of Microunits by Adipose-Derived Mesenchymal Stem Cells Laden with Porous Microcryogels for Repairing an Acute Achilles Tendon Rupture in a Rat Model
por: Yang, Xuan, et al.
Publicado: (2020)

PROMoter uPstream Transcripts share characteristics with mRNAs and are produced upstream of all three major types of mammalian promoters
por: Preker, Pascal, et al.
Publicado: (2011)

Upstream transcription factor 1 prompts malignancies of cervical cancer primarily by transcriptionally activating p65 expression
por: Wang, Wen, et al.
Publicado: (2018)

Etv transcription factors functionally diverge from their upstream FGF signaling in lens development
por: Garg, Ankur, et al.
Publicado: (2020)

Upstream : pre-intermediate
por: Evans, Virginia, 1945-
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_9hv17mr0oki05li2ol8topmoei