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Nanoformulation of D-α-tocopheryl polyethylene glycol 1000 succinate-b-poly(ε-caprolactone-ran-glycolide) diblock copolymer for siRNA targeting HIF-1α for nasopharyngeal carcinoma therapy

Hypoxia-inducible factor-1α (HIF-1α) is a crucial transcription factor that plays an important role in the carcinogenesis and development of nasopharyngeal carcinoma. In this research, a novel biodegradable D-α-tocopheryl polyethylene glycol 1000 succinate-b-poly(ε-caprolactone-ran-glycolide) (TPGS-...

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Detalles Bibliográficos
Autores principales:	Chen, Yuhan, Xu, Gang, Zheng, Yi, Yan, Maosheng, Li, Zihuang, Zhou, Yayan, Mei, Lin, Li, Xianming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337506/ https://www.ncbi.nlm.nih.gov/pubmed/25733830 http://dx.doi.org/10.2147/IJN.S76092

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