The Arf GTPase-Activating Protein Family Is Exploited by Salmonella enterica Serovar Typhimurium To Invade Nonphagocytic Host Cells

To establish intracellular infections, Salmonella bacteria trigger host cell membrane ruffling and invasion by subverting cellular Arf guanine nucleotide exchange factors (GEFs) that activate Arf1 and Arf6 GTPases by promoting GTP binding. A family of cellular Arf GTPase-activating proteins (GAPs) c...

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Detalles Bibliográficos
Autores principales: Davidson, Anthony C., Humphreys, Daniel, Brooks, Andrew B. E., Hume, Peter J., Koronakis, Vassilis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337568/
https://www.ncbi.nlm.nih.gov/pubmed/25670778
http://dx.doi.org/10.1128/mBio.02253-14

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