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A new role for an old enemy

Drugs that change the shape of AKT, a protein kinase that promotes tumor growth, may be more effective than drugs that only target its enzymatic activity.

Detalles Bibliográficos
Autores principales: Monaghan, Richard M, Whitmarsh, Alan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337629/
https://www.ncbi.nlm.nih.gov/pubmed/25668745
http://dx.doi.org/10.7554/eLife.06424
Descripción
Sumario:Drugs that change the shape of AKT, a protein kinase that promotes tumor growth, may be more effective than drugs that only target its enzymatic activity.