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Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs

Existing in vitro models of human skeletal muscle cannot recapitulate the organization and function of native muscle, limiting their use in physiological and pharmacological studies. Here, we demonstrate engineering of electrically and chemically responsive, contractile human muscle tissues (‘myobun...

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Detalles Bibliográficos
Autores principales:	Madden, Lauran, Juhas, Mark, Kraus, William E, Truskey, George A, Bursac, Nenad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Human Biology and Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337710/ https://www.ncbi.nlm.nih.gov/pubmed/25575180 http://dx.doi.org/10.7554/eLife.04885

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