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Angiomotin functions in HIV-1 assembly and budding

Many retroviral Gag proteins contain PPXY late assembly domain motifs that recruit proteins of the NEDD4 E3 ubiquitin ligase family to facilitate virus release. Overexpression of NEDD4L can also stimulate HIV-1 release but in this case the Gag protein lacks a PPXY motif, suggesting that NEDD4L may f...

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Detalles Bibliográficos
Autores principales:	Mercenne, Gaelle, Alam, Steven L, Arii, Jun, Lalonde, Matthew S, Sundquist, Wesley I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337731/ https://www.ncbi.nlm.nih.gov/pubmed/25633977 http://dx.doi.org/10.7554/eLife.03778

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