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Cryptococcus neoformans meningitis with negative cryptococcal antigen: Evaluation of a new immunochromatographic detection assay

Detection of cryptococcal antigen in serum or cerebrospinal fluid allows cryptococcal meningitis diagnosis within few hours with >90% sensitivity. In an HIV-positive patient with Cryptococcus neoformans meningitis, initial antigen detection by immunoagglutination was negative. We thus evaluated a...

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Detalles Bibliográficos
Autores principales: Opota, O., Desgraz, B., Kenfak, A., Jaton, K., Cavassini, M., Greub, G., Prod'hom, G., Giulieri, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337943/
https://www.ncbi.nlm.nih.gov/pubmed/25755893
http://dx.doi.org/10.1016/j.nmni.2014.12.003
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author Opota, O.
Desgraz, B.
Kenfak, A.
Jaton, K.
Cavassini, M.
Greub, G.
Prod'hom, G.
Giulieri, S.
author_facet Opota, O.
Desgraz, B.
Kenfak, A.
Jaton, K.
Cavassini, M.
Greub, G.
Prod'hom, G.
Giulieri, S.
author_sort Opota, O.
collection PubMed
description Detection of cryptococcal antigen in serum or cerebrospinal fluid allows cryptococcal meningitis diagnosis within few hours with >90% sensitivity. In an HIV-positive patient with Cryptococcus neoformans meningitis, initial antigen detection by immunoagglutination was negative. We thus evaluated a new immunochromatographic detection assay that exhibited a higher sensitivity.
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spelling pubmed-43379432015-03-09 Cryptococcus neoformans meningitis with negative cryptococcal antigen: Evaluation of a new immunochromatographic detection assay Opota, O. Desgraz, B. Kenfak, A. Jaton, K. Cavassini, M. Greub, G. Prod'hom, G. Giulieri, S. New Microbes New Infect New Technologies for Infectious and Tropical Diseases Detection of cryptococcal antigen in serum or cerebrospinal fluid allows cryptococcal meningitis diagnosis within few hours with >90% sensitivity. In an HIV-positive patient with Cryptococcus neoformans meningitis, initial antigen detection by immunoagglutination was negative. We thus evaluated a new immunochromatographic detection assay that exhibited a higher sensitivity. Elsevier 2014-12-19 /pmc/articles/PMC4337943/ /pubmed/25755893 http://dx.doi.org/10.1016/j.nmni.2014.12.003 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle New Technologies for Infectious and Tropical Diseases
Opota, O.
Desgraz, B.
Kenfak, A.
Jaton, K.
Cavassini, M.
Greub, G.
Prod'hom, G.
Giulieri, S.
Cryptococcus neoformans meningitis with negative cryptococcal antigen: Evaluation of a new immunochromatographic detection assay
title Cryptococcus neoformans meningitis with negative cryptococcal antigen: Evaluation of a new immunochromatographic detection assay
title_full Cryptococcus neoformans meningitis with negative cryptococcal antigen: Evaluation of a new immunochromatographic detection assay
title_fullStr Cryptococcus neoformans meningitis with negative cryptococcal antigen: Evaluation of a new immunochromatographic detection assay
title_full_unstemmed Cryptococcus neoformans meningitis with negative cryptococcal antigen: Evaluation of a new immunochromatographic detection assay
title_short Cryptococcus neoformans meningitis with negative cryptococcal antigen: Evaluation of a new immunochromatographic detection assay
title_sort cryptococcus neoformans meningitis with negative cryptococcal antigen: evaluation of a new immunochromatographic detection assay
topic New Technologies for Infectious and Tropical Diseases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337943/
https://www.ncbi.nlm.nih.gov/pubmed/25755893
http://dx.doi.org/10.1016/j.nmni.2014.12.003
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