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Challenges of Correlating pH Change with Relief of Clinical Symptoms in Gastro Esophageal Reflux Disease: A Phase III, Randomized Study of Zegerid versus Losec

BACKGROUND: Zegerid (on demand immediate-release omeprazole and sodium bicarbonate combination therapy) has demonstrated earlier absorption and more rapid pH change compared with Losec (standard enteric coated omeprazole), suggesting more rapid clinical relief of heartburn. This Phase III, multicent...

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Detalles Bibliográficos
Autores principales:	Walker, Dave, Ng Kwet Shing, Richard, Jones, Deborah, Gruss, Hans-Jurgen, Reguła, Jarosław
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338010/ https://www.ncbi.nlm.nih.gov/pubmed/25706883 http://dx.doi.org/10.1371/journal.pone.0116308

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