Two Classes of Bacterial IMPDHs according to Their Quaternary Structures and Catalytic Properties

Inosine-5′-monophosphate dehydrogenase (IMPDH) occupies a key position in purine nucleotide metabolism. In this study, we have performed the biochemical and physico-chemical characterization of eight bacterial IMPDHs, among which six were totally unexplored. This study led to a classification of bac...

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Detalles Bibliográficos
Autores principales: Alexandre, Thomas, Rayna, Bertrand, Munier-Lehmann, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338043/
https://www.ncbi.nlm.nih.gov/pubmed/25706619
http://dx.doi.org/10.1371/journal.pone.0116578

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