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Cross-Sectional Comparison of Small Animal [(18)F]-Florbetaben Amyloid-PET between Transgenic AD Mouse Models

We aimed to compare [(18)F]-florbetaben PET imaging in four transgenic mouse strains modelling Alzheimer’s disease (AD), with the main focus on APPswe/PS2 mice and C57Bl/6 mice serving as controls (WT). A consistent PET protocol (N = 82 PET scans) was used, with cortical standardized uptake value ra...

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Detalles Bibliográficos
Autores principales: Brendel, Matthias, Jaworska, Anna, Grießinger, Eric, Rötzer, Christina, Burgold, Steffen, Gildehaus, Franz-Josef, Carlsen, Janette, Cumming, Paul, Baumann, Karlheinz, Haass, Christian, Steiner, Harald, Bartenstein, Peter, Herms, Jochen, Rominger, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338066/
https://www.ncbi.nlm.nih.gov/pubmed/25706990
http://dx.doi.org/10.1371/journal.pone.0116678