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Analysis of Cathepsin and Furin Proteolytic Enzymes Involved in Viral Fusion Protein Activation in Cells of the Bat Reservoir Host
Bats of different species play a major role in the emergence and transmission of highly pathogenic viruses including Ebola virus, SARS-like coronavirus and the henipaviruses. These viruses require proteolytic activation of surface envelope glycoproteins needed for entry, and cellular cathepsins have...
Autores principales: | El Najjar, Farah, Lampe, Levi, Baker, Michelle L., Wang, Lin-Fa, Dutch, Rebecca Ellis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338073/ https://www.ncbi.nlm.nih.gov/pubmed/25706132 http://dx.doi.org/10.1371/journal.pone.0115736 |
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