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Identification of a key residue in K(v)7.1 potassium channel essential for sensing external potassium ions
K(v)7.1 voltage-gated K(+) (K(v)) channels are present in the apical membranes of marginal cells of the stria vascularis of the inner ear, where they mediate K(+) efflux into the scala media (cochlear duct) of the cochlea. As such, they are exposed to the K(+)-rich (∼150 mM of external K(+) (K(+)(e)...
Autores principales: | Wang, Wenying, Flores, Maria Cristina Perez, Sihn, Choong-Ryoul, Kim, Hyo Jeong, Zhang, Yinuo, Doyle, Karen J., Chiamvimonvat, Nipavan, Zhang, Xiao-Dong, Yamoah, Ebenezer N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338162/ https://www.ncbi.nlm.nih.gov/pubmed/25712016 http://dx.doi.org/10.1085/jgp.201411280 |
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