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Evaluation of Canonical siRNA and Dicer Substrate RNA for Inhibition of Hepatitis C Virus Genome Replication – A Comparative Study

Hepatitis C virus (HCV) frequently establishes persistent infections in the liver, leading to the development of chronic hepatitis and, potentially, to liver cirrhosis and hepatocellular carcinoma at later stages. The objective of this study was to test the ability of five Dicer substrate siRNAs (Ds...

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Detalles Bibliográficos
Autores principales: Carneiro, Bruno, Braga, Ana Cláudia Silva, Batista, Mariana Nogueira, Harris, Mark, Rahal, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338191/
https://www.ncbi.nlm.nih.gov/pubmed/25705875
http://dx.doi.org/10.1371/journal.pone.0117742